Endocrine Abstracts

Introduction: Finding the optimal levothyroxine (LT4) dose regime to ameliorate the abnormally low levels of natural thyroid hormones, especially for thyroidectomized patients, is still challenging. Many researchers have studied various LT4 dosage regimen clinically; and ultimately, they proposed multiple variables affecting LT4 requirements including age, gender, body weight, body mass index (BMI), and body surface area (BSA). However, prescribing the most appropriate LT4 dos...

Introduction: Several levothyroxine (LT4) monotherapy dose regimen have been already proposed by different medical scientists which may result in various daily LT4 doses. Comparing the consequences of such dose regimen are rather difficult since they have to be applied on either the same patient or a large study groups. Therefore, a straight forward method would be to simulate the plasma level of thyroid hormones of virtual-patients treated by various dose regimen.<p class...

Introduction: Hyperparathyroidism happens when one or more of parathyroid glands secret excessive parathyroid hormone, causing calcium levels in blood to rise. A diagnosis may be missed or delayed because there are no symptoms or they are vague, like depression, tiredness, losing your appetite in addition to hypercalcaemia symptoms e.g. vomiting, bone and joint pain, dehydration, hypertension, etc. Surgery to remove the parathyroid gland is usually the only way of treating pri...

Background and objectives: Goitre is still one of endemic health problems in Gorgan city after one decade of universal salt iodization in Iran. Hypothyroism have different complications in children that between them, developmental disorders of CNS are so important. This study proposed to determine that prevalence of thyroid function and volume disorders and its correlation with IQ in the mental retard (MR) children.Material and methods: This cross-sectio...

Introduction: Cardiac complications are one of the most important long-term adverse effects of diabetes mellitus (DM), which is usually under diagnosed, as it is frequently asymptomatic. As it seems that the control of DM in developing nations is not optimal, it can be predicted that the prevalence of cardiac complications of DM is subsequently high. We assessed the prevalence of such complications in a developing community in the north of Iran.Method: T...